dAux orchestrates the phosphorylation-dependent assembly of the lysosomal V-ATPase in glia and contributes to α-synuclein degradation

( Autophagy . accepted)   Article Link

Shiping Zhang, Linfang Wang, Shuanglong Yi, Yu-ting Tsai, Honglei Wang, Shuhua Li, Ruiqi Wang, Yang Liu, Wei Yan, Chang Liu, Kai-Wen He, Margaret S. Ho

Behavior- and circuit-specific cortico-striatal decoupling during the early development of Parkinson's disease-like syndrome

( bioRxiv 2024, Under revision in npj Parkinson's Disease . 2024)  Article Link

X-R Yao, Y Liu, W-T Zheng, K-W He*

Pericyte signaling via soluble guanylate cyclase shapes the vascular niche and microenvironment of tumors

( EMBO J . 2024 Apr;43(8):1519-1544. doi: 10.1038/s44318-024-00078-5)  Article Link

Zhu J, Yang W, Ma J, He H, Liu Z, Zhu X, He X, He J, Chen Z, Jin X, Wang X, He K, Wei W, Hu J

RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT

( Proc Natl Acad Sci U S A . 2024 Feb 6;121(6):e2320383121. doi: 10.1073/pnas.2320383121)  Article Link

Cao Z, Min X, Xie X, Huang M, Liu Y, Sun W, Xu G, He M, He K*, Li Y, Yuan J*

Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging

( Nat Struct Mol Biol . 2024 Feb;31(2):232-245. doi: 10.1038/s41594-023-01163-9)  Article Link

Guo R, Liu J, Min X, Zeng W, Shan B, Zhang M, He Z, Zhang Y, He K, Yuan J, Xu D

miR-34a regulates silent synapse and synaptic plasticity in mature hippocampus

( Progress in Neurobiology . 2023 Jan 12;102404. doi: 10.1016/j.pneurobio.2023.102404)  Article Link

X Min, J-Y Wang, F-J Zong, J Zhao, N Liu, K-W He*

Circadian time- and sleep-dependent modulation of cortical parvalbumin-positive inhibitory neurons

( EMBO J . 2022 Dec 7;e111304. doi: 10.15252/embj.2022111304)  Article Link

F-J Zong, X Min, Y Zhang, Y-K Li, X-T Zhang, Y Liu, K-W He*

Brain region-specific synaptic function of FUS underlies the FTLD-linked behavioral disinhibition.

( Brain . 2022 Nov 8;awac411. doi: 10.1093/brain/awac411)  Article Link

J-Y Wang, G-M Ma, X-Q Tang, Q-L Shi, M-C Yu,M-M Lou, K-W He*, W-W Wang*


A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity

( Front Synaptic Neurosci . 2021;13:703621. doi: 10.3389/fnsyn.2021.703621)  Article Link

Mihalas S, Ardiles A, He K, Palacios A, Kirkwood A

Wild-type α-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.

( PNAS . 2021 May 18;118(20):e2012435118. doi: 10.1073/pnas.2012435118)  Article Link

Long H¶, Zheng W¶, Liu Y, Sun Y, Zhao K, Liu Z, Xia W, Lv S, Liu Z, Li D, He K-W*, Liu C*

Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

( Nat Commun . 2021 Jul 15;12(1):4343. doi: 10.1038/s41467-021-24672-x)  Article Link

Li T, Yin Y, Zhou Z, Qiu J, Liu W, Zhang X, He K, Cai Y, Zhu ZJ

Daily Oscillation of the Excitation-Inhibition Balance in Visual Cortical Circuits.

( Neuron . 2020 Feb 19;105(4):621-629.e4. doi: 10.1016/j.neuron.2019.11.011)  Article Link

M Bridi.¶, F-J Zong.¶, X Min N Luo, T Tran, J Qiu, D Severin, X-T Zhang, G Wang, Z-J Zhu, K-W He*, A Kirkwood*

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